USC star sophomore JuJu Watkins suffered a serious injury in the No. 1-seed Trojans’ second-round March Madness win over No. 9-seed Mississippi State on Monday, putting a dismal stamp on the final day of the 2024/25 NCAA tournament's first weekend.
After taking contact from two defenders midway through the first quarter, a visibly distraught Watkins crumbled to the court with a season-ending ACL tear in her right knee. The season's second-leading Division I scorer will soon undergo surgery before beginning rehabilitation.
"I'd be lying if I told you I wasn’t rattled seeing JuJu lying on the floor and crying," said USC head coach Lindsay Gottlieb afterwards. "This is a human game, so I obviously tried my best to be what I need to be for the team, but internally it’s a lot."
The arena mirrored Gottlieb's reaction, a testament to Watkins's impact on the USC community.
"You cannot tell me the energy of that crowd, and how sort of angry they were with the other team, and how much fire they showed for our team, is so much about what JuJu has given to this arena, to this program, to the city," added Gottlieb. "And you just want to give it all back."
A National Player of the Year frontrunner, Watkins’s injury will reverberate throughout USC’s tournament run, as the Trojans stare down a potential Elite Eight rematch with surging No. 2-seed UConn.

Trojans step up after Watkins injury
After seeing their teammate carried off the court, USC regrouped in a big way, converting their early 13-2 lead into a 96-59 blowout victory over the Bulldogs to clinch a spot in the Sweet 16.
In light of the Watkins injury, star transfer forward Kiki Iriafen took charge, putting up a season-high 36 points and nearly notching a double-double by adding nine rebounds to her stat sheet.
Also taking up Watkins' mantle were a pair of freshmen guards, Avery Howell and Kayleigh Heckel, who came off the bench to add 18 and 13 points, respectively.
The added emotional tenacity the Trojans displayed was not lost on Gottlieb, who thanked her team in a post-game locker room address.
"I will never forget this game for as long as I live," the USC coach told her players. "You guys did something really special today."
"I have to say it with a calm face and tell you how incredibly proud I am of the way you stepped up for one another...it was a tidal wave of a team."
Top NCAA tournament seeds dominate Sweet 16 berths
Ultimately, losing Watkins is a devastating blow not just to USC, but to college basketball at large, radically reshaping the competitive landscape as March Madness gears up for next weekend's Sweet 16 round.
Monday's final buzzer officially set that field, locking in every team seeded No. 3 and above, plus one No. 4 seed and a trio of No. 5 seeds.
In a day void of upsets, seven of Monday's games averaged a wide 28-point margin of victory. The lone outlier was Maryland's bombshell victory, as the Terps booked their Sweet 16 spot in an instant classic game against No. 5-seed Alabama.
After the Terrapins rallied from a 17-point third-quarter deficit to push the game into overtime, Tide fifth-year guard Sarah Ashlee Barker forced double-overtime with a trio of free throws.
Though the Terps ultimately emerged with the 111-108 victory, Barker set records, notching a career-high 45 points — the most by any SEC athlete and the fourth-most by any Division I player in March Madness history.
"It didn't go our way but, at the end of the day, I'm gonna walk out and hold [my] head high," said Barker about the game that capped her NCAA career. "If you're a women's basketball fan, or anybody that loves basketball, I think that every single person could say that that was one of the best games they've ever watched."
With games between the NCAA's best stacking next weekend's Sweet 16 slate, this year's March Madness tournament is could see even more blockbuster clashes.