March Madness opens its doors on Wednesday night, as the 2024/25 NCAA tournament’s First Four round takes the court with eight teams pursuing the final four tickets to the Big Dance.

Two of the play-in games will pit the last four teams to receive at-large bids against each other, sending Princeton, Iowa State, Washington, and Columbia into battle to snag one of the tournament's final two No. 11 bids.

The other two games are comprised of the lowest ranked conference tournament champions, meaning SWAC champ Southern, Big West winner UC San Diego, CAA victors William & Mary, and Big South title-holders High Point will all compete to enter this weekend's first round as No. 16 seeds.

UC San Diego's Sabrina Ma celebrates the 2025 Big West tournament win that sent her team to their first-ever March Madness.
UC San Diego will make their March Madness debut in Wednesday's First Four round. (Ian Maule/Getty Images)

First Four ups the ante with compelling NCAA storylines

Thanks to growing parity across the NCAA, this year’s First Four brings a new level of heat, with 2024 breakout stars, conference titans, and tournament newcomers raising the stakes right from the jump.

As two of 2025’s six March Madness debutants, both UC San Diego and William & Mary are hoping for a bit of beginner's luck as they take the NCAA tournament court for the very first time.

Meanwhile, the Ivy League will take aim at securing three spots in the 64-team bracket, with both Princeton and Columbia hoping to join conference tournament champion No. 10 seed Harvard in the first round's field.

Standing in Princeton's way is underdog Iowa State, who nearly scored what would have been one of the 2024 tournament's biggest upsets.

Fueled by now-sophomore sharpshooter Audi Crooks — who currently ranks 12th in the nation in field goal percentage — the Cyclones pushed then-No. 2 seed Stanford to the brink, forcing overtime before the Cardinal claimed the 87-81 second-round victory.

"It’s definitely possible," Crooks said this week, commenting on the likelihood of replicating Iowa State's 2024 run. "I think for me it just amplified me personally, and also us as a team. Any success that I have is the team’s success, not necessarily about individual things."

The Princeton bench celebrates a basket during the 2024 March Madness tournament.
Princeton and Iowa State will tip off March Madness's First Four round on Wednesday. (Keith Gillett/Icon Sportswire via Getty Images)

How to watch Women's March Madness First Four games

Stepping into Wednesday's spotlight are Princeton and Iowa State, who will take the court at 7 PM ET before UC San Diego takes on Southern at 9 PM ET.

Then on Thursday, Washington will face Columbia at 7 PM ET, with William & Mary's match against High Point wrapping up the First Four round at 9 PM ET.

Both Wednesday matchups will air on ESPNU, with ESPN2 carrying live coverage of the Thursday clashes.

NCAA basketball teams traveled to off-campus mini-tournaments during last week's Thanksgiving break, with results showing that some teams feasted while others fought over leftovers.

Reigning national champions South Carolina went on a redemption tour at the Fort Myers Tip-Off, while Notre Dame struggled at the Cayman Islands Classic.

Notre Dame star Hannah Hidalgo looks up in frustration during a women's college ncaa basketball game.
The Irish followed a big win against USC with two straight losses. (MICHAEL CLUBB/SOUTH BEND TRIBUNE/USA TODAY NETWORK)

Notre Dame drops two NCAA basketball games in a row

Following last week's huge win against title contender No. 6 USC, then-No. 3 Notre Dame hit an unexpected skid over the weekend, falling first 76-68 to then-No. 17 TCU on Friday before further stumbling 78-67 against unranked Utah on Saturday.

Star guard Hannah Hidalgo's 27 points weren't enough to topple the Horned Frogs, who saw center Sedona Prince and guards Hailey Van Lith and Madison Connor put up a combined average of almost 20 points in the Friday battle.

Similarly, though Notre Dame junior guard Sonia Citron's 22 points made her the only player on either team to sink more than 16 points on Saturday, the Utes' team effort won the day. Seven Utah athletes drained at least five points, with four notching double-digits.

"I just thought today our depth hurt us with our foul trouble, and consecutive games back-to-back against two really good teams," head coach Niele Ivey said of the Irish's first successive losses since 2021.

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South Carolina bounces back in style

On the other hand, then-No. 4 South Carolina bounced back big time from their first regular-season loss since 2022 on Thursday, defeating then-No. 15 Iowa State 76-36 to right the ship after last weekend's UCLA upset.

The Gamecocks' defense controlled the floor throughout the first half, allowing just nine points from the Cyclones while nine different South Carolina players scored.

Only four Iowa State players put up points in the matchup, with sophomore star Audi Crooks shooting far below her season average at just 13 points.

"Obviously, there were some lapses in the UCLA game that weren't characteristic of us," commented South Carolina head coach Dawn Staley. "That is our nemesis — to be able to lock in on both sides of the ball and not have as many lapses or put them on the free-throw line as much as we did."

South Carolina continued making a statement on Saturday, when 11 Gamecocks — including seven double-digit scorers — combined to handily defeat Purdue 99-51.

TCU guard Hailey Van Lith drive to the basket during a college ncaa basketball game.
No. 9 TCU jumped eight AP poll spots Monday to their first-ever Top 10 ranking. (Ron Jenkins/Getty Images)

Early season losses shake up NCAA basketball rankings

With five teams from last week's AP Top 10 already racking up early non-conference losses, Monday's Top 25 reflected the chaos.

Notre Dame plummeted seven spots to No. 7 thanks to their stalled weekend offense, while South Carolina leveled up to No. 3 with their weekend wins. After suffering the 40-point blowout loss to the Gamecocks, Iowa State took the week's second-biggest tumble, dropping five spots to No. 20.

UCLA maintained their grip on No. 1 after complementing last week's upset over reigning champs South Carolina with three additional wins, with No. 2 UConn holding steady just behind the Bruins.

The week's biggest riser was TCU, whose victory over the Irish launched them eight spots to No. 9 — the program's first-ever Top 10 ranking.

Boosting the Big Ten to a league-leading nine ranked teams this week is poll season debutants and state rivals No. 23 Michigan and No. 24 Michigan State, who make their first AP appearances since 2023 and 2021, respectively.

How to watch NCAA women's basketball this week

Monday's rankings raised the stakes in this week's matchups, with two Top 10 games emerging on Thursday's docket.

First, No. 4 Texas will put their undefeated season on the line against the skidding No. 10 Notre Dame at 7 PM ET. Live coverage will air on ESPN.

Then, No. 3 South Carolina will host new-No. 8 Duke, who'll take aim at the Gamecocks' win-streak recovery at 9 PM ET, also airing on ESPN.