March Madness opens its doors on Wednesday night, as the 2024/25 NCAA tournament’s First Four round takes the court with eight teams pursuing the final four tickets to the Big Dance.

Two of the play-in games will pit the last four teams to receive at-large bids against each other, sending Princeton, Iowa State, Washington, and Columbia into battle to snag one of the tournament's final two No. 11 bids.

The other two games are comprised of the lowest ranked conference tournament champions, meaning SWAC champ Southern, Big West winner UC San Diego, CAA victors William & Mary, and Big South title-holders High Point will all compete to enter this weekend's first round as No. 16 seeds.

UC San Diego's Sabrina Ma celebrates the 2025 Big West tournament win that sent her team to their first-ever March Madness.
UC San Diego will make their March Madness debut in Wednesday's First Four round. (Ian Maule/Getty Images)

First Four ups the ante with compelling NCAA storylines

Thanks to growing parity across the NCAA, this year’s First Four brings a new level of heat, with 2024 breakout stars, conference titans, and tournament newcomers raising the stakes right from the jump.

As two of 2025’s six March Madness debutants, both UC San Diego and William & Mary are hoping for a bit of beginner's luck as they take the NCAA tournament court for the very first time.

Meanwhile, the Ivy League will take aim at securing three spots in the 64-team bracket, with both Princeton and Columbia hoping to join conference tournament champion No. 10 seed Harvard in the first round's field.

Standing in Princeton's way is underdog Iowa State, who nearly scored what would have been one of the 2024 tournament's biggest upsets.

Fueled by now-sophomore sharpshooter Audi Crooks — who currently ranks 12th in the nation in field goal percentage — the Cyclones pushed then-No. 2 seed Stanford to the brink, forcing overtime before the Cardinal claimed the 87-81 second-round victory.

"It’s definitely possible," Crooks said this week, commenting on the likelihood of replicating Iowa State's 2024 run. "I think for me it just amplified me personally, and also us as a team. Any success that I have is the team’s success, not necessarily about individual things."

The Princeton bench celebrates a basket during the 2024 March Madness tournament.
Princeton and Iowa State will tip off March Madness's First Four round on Wednesday. (Keith Gillett/Icon Sportswire via Getty Images)

How to watch Women's March Madness First Four games

Stepping into Wednesday's spotlight are Princeton and Iowa State, who will take the court at 7 PM ET before UC San Diego takes on Southern at 9 PM ET.

Then on Thursday, Washington will face Columbia at 7 PM ET, with William & Mary's match against High Point wrapping up the First Four round at 9 PM ET.

Both Wednesday matchups will air on ESPNU, with ESPN2 carrying live coverage of the Thursday clashes.

The 2024/25 NCAA basketball tournament bracket is officially locked in, as Selection Sunday saw March Madness favorites, underdogs, and a few surprises claim their tickets to the Big Dance.

After winning the Big Ten tournament one week prior, UCLA not only earned the NCAA competition's overall top spot, but the Bruins claimed their first-ever No. 1 seed in program history.

Sitting atop the three other quadrants are SEC tournament title-winners and NCAA defending champions South Carolina as well as conference runners-up Texas and USC, giving both the SEC and Big Ten two of the tournament's top contenders.

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Chasing the four top teams as No. 2 seeds are Big 12 tournament champs TCU, ACC tournament winners Duke, ACC runners-up NC State, and Big East champions UConn, whose late-season momentum wasn't quite enough to life the Huskies above a second-spot bid.

In a season that saw a record-tying four teams reach No. 1 in the AP Poll, three (UCLA, South Carolina, and Texas) claimed NCAA No. 1 seeds, with once-No. 1 ranked Notre Dame falling out of top-seed contention after losing three of their last five games.

The Irish will now tip off their March Madness campaign as a No. 3 seed alongside 2022/23 NCAA champs LSU, North Carolina, and Oklahoma.

Snagging the tournament's last hosting spots are the No. 4 seeds, meaning Ohio State, Kentucky, Baylor, and Maryland will all have home-court advantage through the competition’s first two rounds.

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Coaches question NCAA committee's seeding decisions

While some teams were thrilled with their placements, a tinge of disappointment overshadowed other top contenders’ watch parties.

"I never thought I'd be a No. 1 seed and feel disrespected," said USC head coach Lindsay Gottlieb after learning the NCAA committee awarded the Trojans the last top seed, ranking them fourth overall.

"It's not an arrogance of any kind, I think that there's a lot of really good teams...but I would love to ask [this committee] some questions."

Head coach Dawn Staley had a similar reaction to South Carolina's positioning, saying "I'm a little bit surprised."

"I'd like to get some feedback on how they came to that conclusion," said Staley. "We put together, manufactured, a schedule that — if done right — should produce the overall No. 1 seed."

The NCAA committee broke down their determination of the Gamecocks on ESPN, explaining that South Carolina’s head-to-head November loss to UCLA plus last month's 29-point nonconference defeat at the hands of UConn played major roles in the decision.

Despite the disappointment, Gottlieb says her team is ready to take care of business.

"You've gotta play the first game in front of you and earn your way from there, and that's what we'll do."

Iowa's Hannah Stuelke defends Michigan State's Julia Ayrault during a 2025 Big Ten basketball tournament game.
The Big Ten has more teams in the March Madness bracket than any conference in NCAA history. (Michael Hickey/Getty Images)

Big Ten makes NCAA March Madness bracket history

With 12 teams booking spots in the Big Dance, the Big Ten not only earned the season’s most NCAA tournament bids, it also smashed the Division I record for the most programs in a single conference to make a March Madness bracket.

With a conference-record 10 teams, the SEC closely followed the Big Ten, while eight ACC squads and seven Big 12 programs round out the Power Four's 37 total berths.

Also experiencing a record-setting Selection Sunday was the Ivy League, which saw three teams sneak into the competition for the first time in the eight-program conference's history.

After upsetting their way through last weekend's conference competition, Ivy League tournament champions Harvard secured a No. 10 seed on Sunday, while both Columbia and Princeton have a shot at snagging a No. 11 seed as contenders in the NCAA's First Four games.

Dancing for the first time are six teams, with Arkansas State, Fairleigh Dickinson, George Mason, Grand Canyon, UC San Diego, and William & Mary all set to make their NCAA tournament debuts later this week.

To be the best, teams must beat the best, and the talent concentrated at the top of the NCAA bracket — regardless of seeding — is guaranteed to make for some tough competition.

Iowa State basketball star Audi Crooks shoots a free throw during a 2025 Big 12 tournament game.
Iowa State will tip off against Princeton in the 2025 NCAA tournament's First Four round. (Amy Kontras/Imagn Images)

How to watch the First Four March Madness games

While the the official first round of the 2024/25 NCAA basketball tournament doesn't begin until Friday, the March Madness action will tip off with the First Four round on Wednesday, when eight teams will battle for the final four spots in the 64-team bracket.

Stepping into Wednesday's spotlight are Princeton and Iowa State, who will take the court at 7 PM ET before UC San Diego takes on Southern at 9 PM ET.

Then on Thursday, Washington will face Columbia at 7 PM ET, with William & Mary's match against High Point wrapping up the First Four round at 9 PM ET.

The Huskies' Thursday clash with the Lions will air live on ESPN2, with the other three First Four games earning live coverage on ESPNU.

Print complete NCAA Women's March Madness bracket

Printable complete NCAA Women's March Madness bracket.